A Complete Genomic Data Platform for Clinical Excellence
Frameshift was created by members of the Molecular Tumor Board at Duke University to optimize patient-centered precision cancer medicine by connecting patients to treatment with real-time decision support.
Data Normalization
Standardizes genomic testing data from different vendors
Creates unified data format for consistent analysis
Eliminates data silos between testing platforms
Robust Searching & Filtering
Enables complex queries across normalized genomic data
Allows filtering by multiple parameters simultaneously
Supports rapid identification of relevant patient cohorts
Patient Case Presentation
Facilitates collaborative review of patient genomic profiles
Supports multidisciplinary team discussions
Enables knowledge sharing across clinical teams

Update cancer therapy as soon as new treatments are available. Connect patients with clinical trials in a heartbeat.
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Clinical researchers can easily look up patients by genetic mutation and other criteria to find every potentially qualified patient within the hospital system, and match them with available clinical trials.
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Molecular Tumor Boards (MTBs) can use Frameshift to aid in case selection, case presentation, decision documentation, follow-ups, and tracking outcomes. Preparing for meetings is more efficient, and discussions are more collaborative.
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Pharmaceutical Companies can cover implementation costs at a hospital to aid in identifying patient eligibility for newly-approved therapies and clinical trials. Providers receive an alert when your therapies are FDA-approved and helps to identify potential candidates for your therapy. Boost efficiency and patient outcomes.
Extend your EHR with Frameshift and unlock high-powered insights
Make better patient outcomes a reality
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Frameshift aggregates, normalizes, and standardizes next gen sequencing report data from several commercial vendors, including Foundation, Guardant, and Caris.
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Frameshift offers facilitation tools for Molecular Tumor Board (MTB) review meetings, from selecting patients for review to serving as a presentation medium.
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Frameshift provides real-time notifications when results become available that can guide patient care, inform follow-ups, and improve outcomes.
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Identify a cohort of patients based on molecular signature, demographics, and other health information.
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Your organization’s data is kept siloed and independent from other organizations. Control which of your users may view Protected Health Information (PHI) and which may not.
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Pull data from EPIC including patient demographics, patient deaths, and molecular data.
Gain access to real-world clinic-genomic data
AACR Project GENIE has collected genomic data from over 80,000 patients with advanced or rare cancers, making it one of the largest cancer genomic datasets available. Frameshift empowers you to:
Seamlessly integrate with AACR Project GENIE, the largest publicly accessible cancer registry of real-world clinic-genomic data
Save hours of tedious manual work by easily downloading and uploading data for Project GENIE
Improve patient care and outcomes by utilizing the wealth of real-world data available through Project GENIE
Tap into this vast pool of knowledge to drive better patient outcomes.